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"We met with several extremely capable consultancy firms who had extensive experience in this field of devices, but PA  impressed us most with their expertise and hands on approach. 

IAN PALING, CHAIRMAN AND CEO, CELLCOTEC

CellCoTec - automating a lab-based process, improving cell yield, reducing process times

CellCoTec is a development stage orthopaedics company developing a ground breaking tissue regeneration therapy to provide a unique single-surgery procedure for repair of damaged articular cartilage in the knee. To realise their  aspirations, CellCoTec wanted to automate their lab based process, improve the cell yield and continue to reduce process times. PA were chosen to deliver this novel project because of their unique blend of development capabilities and  approach to implementation not found in other consultancies.  The first stage of the work was recently completed by PA.

The project required complex and delicate manipulation and processing of cells in both large and small volumes of fluid.  This provided PA with many challenges which they addressed by creating a diverse project team who worked intimately with CellCoTec's management and lab teams.

PA's team included life scientists to advise on the intricacies and nuances of cell handling and enzyme digestion, while our manufacturing process improvement team created novel machine concepts to  overcome the technical challenges.

PA facilitated workshops and team meetings to discuss and agree options, priorities and areas of uncertainty.  This work was combined with practical engineering and rapid prototyping to build proof-of-principle test rigs which CellCoTec could evaluate in the laboratory.

PA has a proven track record in taking lab-based processes and successfully and efficiently developing them into automated procedures with reduced process times.

Ian Paling, Chairman and CEO of CellCoTec said: "the Cell Processor is a fundamental element of our commercialisation strategy and we are delighted with the work that PA has carried out to date."

CellCoTec have posted news of their project with PA on their website: http://www.cellcotec.com/news.php#38

To find out more about automating lab-based processes, please contact us now.